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Indications of Vemurafenib

1. Unresectable or Metastatic Melanoma

Vemurafenib is indicated for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E mutation as detected by an FDA-approved test.

Limitation of Use: Vemurafenib is not indicated for treatment of patients with wild-type BRAF melanoma.  

2. Erdheim-Chester Disease

Vemurafenib is indicated for the treatment of patients with Erdheim-Chester Disease (ECD) with BRAF V600 mutation.

from FDA,2020.12

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