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Release date: 2024-08-16 16:19:21 Recommended: 144
By inhibiting the synthesis of adrenocortical hormones, Mitotane slows or stops the growth of tumor cells and improves related symptoms to some extent.
Mitotane is mainly suitable for patients with the following diseases:
Mitotane is a drug used to treat functional adrenocortical carcinoma (ACC). It is able to slow or stop the growth of tumor cells by inhibiting the synthesis of adrenocortical hormones. For patients with adrenocortical carcinoma that cannot be removed surgically or have distant metastases, Mitotane has shown some therapeutic effects, prolonging survival and improving quality of life.
Mitotane is also used to treat hypercortisolism caused by adrenal hyperplasia or tumors. Hypercortisolism can cause high levels of cortisol in the body, which can lead to a series of symptoms, such as central obesity, moon face, buffalo back, etc. By inhibiting the synthesis and secretion of adrenal corticosteroids, Mitotane helps to reduce cortisol levels in the body, thereby alleviating these symptoms.
The neuromuscular toxicity of Mitotane is one of the serious problems that can occur during its treatment.
Patients may experience symptoms such as drowsiness, dizziness, headaches, etc., affecting daily life and cognitive performance. More severe neurotoxic reactions include confusion, muscle tremors, fatigue, ataxia, and dysarthria, which can severely affect balance, coordination, and speech.
In view of the neuromuscular toxicity and adverse reactions that may be caused by Mitotant, the following are three countermeasures:
Patients should inform their doctor immediately if they experience symptoms of neuromuscular toxicity such as drowsiness, dizziness, and muscle tremors while taking Mitotane. Depending on the patient's specific situation, doctors will consider whether the drug dose needs to be adjusted, the treatment regimen changed, or other interventions needed to reduce or eliminate these adverse effects.
Regular neurological examinations, including assessment of the patient's mental state, muscle strength, coordination, etc., can help identify potential neuromuscular toxicity problems early. The doctor will also adjust the treatment plan in time according to the changes in the patient's symptoms to ensure the safety and effectiveness of the treatment.
For patients with adverse effects of neuromuscular toxicity, it is important to maintain adequate rest and appropriate rehabilitation. With reasonable rest, the burden on the nervous system can be reduced and the normal function of the neuromuscular can be restored. Proper rehabilitation training can enhance muscle strength, improve coordination, and further improve patients' symptoms and quality of life.
【Warm tips】When patients buy generic drugs, they should choose formal channels to ensure the quality and safety of the drugs. Avoid purchasing counterfeit products from informal sources.
