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What are the side effects of using Alpelisib?

Release date: 2024-12-20 13:10:25     Recommended: 78

Alpelisib, an innovative targeted therapy drug, brings new hope for specific types of breast cancer patients. However, like many powerful drugs, apellix can be accompanied by a range of side effects. So, what are the side effects of using Apellix?

What are the side effects of using Alpelisib?

The side effects of apellix are varied, and patients need to pay close attention.

Blood glucose fluctuations: include elevated and low blood glucose, and in some cases may cause hyperglycaemic hyperosmolar nonketosis syndrome or ketoacidosis.

Digestive reactions: diarrhea, nausea, vomiting, loss of appetite and stomatitis, etc., which may lead to dehydration in severe cases.

Skin problems: severe skin adverse reactions such as rash, Stevens-Johnson syndrome, erythema multiforme, etc.

Hematologic abnormalities: decreased lymphocyte count, low hemoglobin, etc.

Abnormal liver function: elevated γ-glutamyl transferase, alanine aminotransferase, etc.

Others: fatigue, weight loss, calcium loss, prolonged activated partial thromboplastin time, hair loss, etc.

These side effects not only affect the patient's quality of life, but can also pose a challenge to the treatment process.

How to prevent Apellix from having side effects

The key to preventing side effects is early identification and management.

Strictly follow the doctor's instructions: take the medicine on time and in the right amount, and do not increase or decrease the dose at will.

Regular monitoring: Regularly check blood glucose, liver function, blood routine and other indicators to detect abnormalities in time.

Lifestyle modifications: Maintain a healthy diet, exercise moderately, control weight, and avoid obesity.

Avoidance of drug interactions: Know and avoid drug combinations that interact with apellix.

Attention to special populations: pregnant women, lactating women, people with reproductive potential, children and the elderly, etc., need to be cautious in taking medication under the guidance of a doctor.

Through a combination of measures, the risk of side effects of apellix can be effectively reduced.

How to deal with the side effects of Apellix

In the face of side effects, timely response is key.

Hyperglycemia: monitor blood glucose immediately, adjust hypoglycemic drugs as prescribed, and interrupt or taper apellix if necessary.

Diarrhea or colitis: stop diarrhea promptly, increase the volume of oral fluid, adjust the dose of apellix if necessary, or discontinue the drug.

Adverse skin reactions: discontinue the drug immediately and seek professional treatment from a dermatologist.

Pneumonia: Apellix is discontinued immediately upon respiratory symptoms and evaluated for pneumonia.

Other serious side effects: such as allergic reactions, serious adverse skin reactions, etc., need to seek medical attention immediately, and if necessary, permanently stop the drug.

Patients should remain calm, seek medical attention in a timely manner, and work with their doctor to develop coping strategies.

Apellix is an effective drug for the treatment of certain types of breast cancer, and its efficacy is significant, but the side effects cannot be ignored. By understanding side effects and proactively preventing and coping with them, patients can maximize the effectiveness of apellix while maintaining safety. Medical professionals should also continue to pay attention to the patient's physical condition and adjust the treatment plan in a timely manner.