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Adverse reactions of Sotorasib

The most common adverse reactions (≥ 20%) were diarrhea, musculoskeletal  pain, nausea, fatigue, hepatotoxicity, and cough. The most common laboratory  abnormalities (≥ 25%) were decreased lymphocytes, decreased hemoglobin,  increased aspartate aminotransferase, increased alanine aminotransferase,  decreased calcium, increased alkaline phosphatase, increased urine protein,  and decreased sodium. 

from FDA,2023.04

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