Your Health, We Care

Home > Drug List > Sotorasib > Dosage of Sotorasib

What is the prescribed dosage of Sotorasib?

Release date: 2024-07-09 17:13:08     Recommended: 162

Sotorasib represents a groundbreaking targeted therapy that has exhibited remarkable efficacy in combatting non-small cell lung cancer (NSCLC), particularly among individuals harboring KRAS G12C mutations. By precisely thwarting the activity of the KRAS G12C protein, this medication adeptly halts cellular proliferation and dissemination, instilling fresh hope in the realm of therapeutics.

What is the prescribed dosage of Sotorasib?

The recommended dosage of Sotorasib stands at 960 mg, corresponding to either three 320 mg tablets or eight 120 mg tablets administered orally on a daily basis. Patients are urged to adhere to their healthcare provider's instructions, ingesting the medication once daily consistently until disease progression or the emergence of intolerable adverse effects. It is imperative for patients to take Sotorasib at a fixed hour each day, ensuring a steady concentration of the drug within the system.

Sotorasib may be administered with or without food, however, regardless of the manner of intake, individuals should consume the tablet whole and refrain from chewing, crushing, or splitting it to preserve the optimal release and absorption of the medication. In instances where a dose of Sotorasib has been missed for over 6 hours, no undue alarm is necessary. Adherence to the prescribed dosing schedule is advised, with the subsequent dose to be taken at the designated time the following day. It is essential to avoid the simultaneous intake of two doses of Sotorasib to compensate for missed administrations.

As a prescription medication, strict adherence to the healthcare provider's guidance is imperative. Patients must adhere to the recommended dosing regimen, administering the drug punctually and in the correct dosage, while refraining from modifying the dosage without prior authorization. Awareness of potential adverse events, contraindications, and drug interactions is warranted prior to initiation of treatment.

Adverse reactions of Sotorasib

The adverse effects of Sotorasib should not be overlooked by patients undergoing treatment with this medication. Though generally well-tolerated in clinical trials, certain individuals may experience the following deleterious consequences:

1. Proteinuria

There exists a possibility that some patients may exhibit heightened levels of protein in their urine, a manifestation that may be attributed to the drug's impact on renal function. Regular urinalysis is recommended for timely detection and efficient management of this complication.

2. Hyponatremia

Sotorasib usage can precipitate a depletion in the concentration of sodium ions within the individual's physiological milieu, culminating in symptoms indicative of hyponatremia such as fatigue, cephalalgia, and emesis. Monitoring of blood sodium levels should be conducted periodically, with adjustments to dietary regimens and medication dosages made under the guidance of healthcare providers.

3. Calcium decreases

Calcium levels may diminish following the administration of Sotorasib, potentially inducing manifestations such as muscular spasms and fasciculations. Individuals are urged to monitor their calcium consumption diligently and incorporate supplements as directed by a medical professional.

[Warm tips] In order to optimize their treatment outcomes, patients are encouraged to cultivate a positive mental attitude and engage in regular physical activity while undergoing Sotorasib therapy. Adherence to medical directives for recuperation is paramount. Scheduled health evaluations are imperative for the identification and mitigation of any foreseeable complications. In the event of any apprehensions or discomfort, it is advised to promptly seek counsel from a healthcare provider.