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What are the side effects of using Pemigatinib?

Release date: 2024-08-14 15:53:57     Recommended: 143

Pemigatinib has demonstrated significant efficacy in the treatment of cholangiocarcinoma with FGFR2 fusion or rearrangement features, among other diseases.

What are the side effects of using Pemigatinib?

There may be a variety of side effects associated with the use of Pemigatinib, which may present differently in different patients.

1. Diarrhea

Diarrhea is one of the most common gastrointestinal reactions to Pemigatinib and may manifest as symptoms such as increased stool frequency and loose stools. Patients are advised to adjust their diet, avoid greasy and spicy foods, and consult their doctor about antidiarrheal medications if necessary.

2. Nausea and vomiting

Some patients may experience nausea and vomiting, which may affect appetite and nutrient intake. Patients are advised to take appropriate measures to alleviate these symptoms under the guidance of their doctor, such as the use of antiemetic medications.

3. Indigestion

Manifested as epigastric discomfort, fullness, etc., may be related to the irritation of the gastrointestinal tract by the drug.

What eye problems can Pemigatinib cause in patients

Pemigatinib is a targeted therapy drug that is primarily used to treat patients with cholangiocarcinoma with specific genetic variants. During use, patients may experience a series of eye problems as adverse reactions.

1. Blurred vision

Patients may have blurred vision, which affects visual clarity. Patients are advised to take care of their eyes during medication and avoid behaviors that may aggravate symptoms, such as prolonged use of electronic products. If symptoms persist or worsen, you should seek medical attention promptly.

2. Dry eyes

Pemigatinib may cause the eyes to feel dry and uncomfortable, requiring the use of artificial tears and other symptoms to relieve symptoms. Patients can choose the right artificial tear product under the guidance of their doctor and follow the correct method of use.

Precautions for eye problems

In order to avoid serious ocular adverse reactions during the treatment of Pemigatinib, the following aspects should be paid attention to during treatment.

Pemigatinib may cause vision problems such as dry eye, retinopathy, etc. Ophthalmologic examinations, including optical coherence tomography (OCT), should be performed before initiation of treatment, every 2 months for the first 6 months of treatment, and every 3 months thereafter.

Patients should consult a doctor immediately if they develop urgent visual symptoms at any time.

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