Release date: 2024-08-13 10:38:07 Recommended: 169
Pemigatinib is mainly used to treat specific diseases such as advanced or metastatic cholangiocarcinoma caused by FGFR2 fusion or rearrangement.
Pemilitinib is indicated for the treatment of adults with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma with fibroblast growth factor receptor 2 (FGFR2) fusion or other rearrangements detected by FDA-approved assays.
Specifically, it is used to treat patients with cholangiocarcinoma that has metastasized (spread to other parts of the body) or is locally advanced and cannot be treated by surgery, especially those with FGFR2 gene fusions or other changes in the structure of the FGFR2 gene.
In some countries and regions, governments regulate and price drug prices. This pricing policy has a direct impact on the market price of the drug.
Different regions have different levels of economic development, and people's ability to pay is also different. This results in different market prices for the drug in different regions. For imported drugs, import tariffs and exchange rate fluctuations can also affect their prices. Tariff increases and decreases and exchange rate fluctuations will change the cost of importing drugs, which in turn will affect the selling price.
The original drug has patent protection and technical advantages, and the price is usually higher. Generic drugs, on the other hand, are marketed after the patent expires and are relatively inexpensive. There is a significant difference in the price of the original drug and the generic drug of Pemigatinib. The sales channel of a drug can also affect its price. Different sales channels may have different pricing strategies and profit margins.
The production process of the original drug is complex and delicate, and the quality of the excipients used is relatively high. The selection of these production processes and excipients is critical to ensuring the quality and stability of drug products. Although generic drugs are similar in composition to the original drug, their production process and choice of excipients may differ. These differences may lead to differences between the generic drug and the original drug in terms of purity, stability, etc.
The original drug needs to complete the complete new drug application process and implement strict international standards. These standards include a thorough and rigorous review and evaluation of all aspects of a pharmaceutical product. Generic drugs only need to go through the simple new drug application process and the implementation of relatively relaxed standards.
The R&D cost of the original drug is high, the cycle is long the risk is high, and the price is usually high. With the inclusion of some original drugs in the medical insurance catalogue and the implementation of the price negotiation mechanism, their prices have gradually become more affordable. Generic drugs are usually priced lower due to their lower R&D costs and short lead times. This makes generic drugs have a greater advantage in price and are more easily accepted by patients.
【Warm tips】When patients buy generic drugs, they should choose formal channels to ensure the quality and safety of the drugs. Avoid purchasing counterfeit products from informal sources.