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Therapeutic efficacy of Momelotinib

The efficacy of Momelotinib in the treatment of patients with MF in SIMPLIFY-1 was based on spleen volume response (reduction by 35% or greater). A numerically lower percent of patients  treated with Momelotinib (25%) achieved a Total Symptom Score reduction of 50% or more at  Week 24 compared with ruxolitinib (36%).

from FDA,2023.09

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