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Dosage of Macitentan

Recommended DoseThe recommended dose of macitentan is 10 mg orally once daily. Doses higher than 10 mg once daily have not been studied in PAH patients and are therefore not recommended.

Pregnancy Testing for Females of Reproductive PotentialPregnancy must be excluded before initiating macitentan treatment in females of reproductive potential.

FDA,2025.04

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