Common adverse reactions to lorlatinib include:
Swelling of extremities, hands and feet (edema).
Numbness or tingling in joints or extremities (peripheral neuropathy).
Weight gain.
Cognitive impairment (e.g., forgetfulness, confusion).
Fatigue.
Dyspnea.
Arthralgia.
Diarrhea.
Mood changes (e.g., depression, irritability).
Elevated blood lipid levels.
Cough.
In addition, lorlatinib may reduce fertility in males and impair normal reproductive function. If you have concerns about this, consult a healthcare professional.
The above is not an exhaustive list of all adverse reactions to lorlatinib. For more information, consult a healthcare professional or pharmacist.
Seek prompt medical advice if any adverse reaction occurs.
FDA,2021.03