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Adverse reactions of Lorlatinib

The following adverse reactions are described elsewhere in the labeling:

1. Risk of Serious Hepatotoxicity with Concomitant Use of Strong CYP3A Inducers

2. Central Nervous System Effects

3. Hyperlipidemia

4. Atrioventricular Block

5. Interstitial Lung Disease/Pneumonitis

6. Hypertension

7. Hyperglycemia

FDA,2021.03