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Before initiating lenacapavir treatment, healthcare providers should carefully select patients who agree to comply with the required once-every-6-months injection dosing schedule. They should also inform patients of the importance of attending scheduled lenacapavir dosing visits and adhering to the combined oral antiretroviral therapy. This helps maintain viral suppression and reduces the risk of viral rebound and potential development of drug resistance due to missed doses.
The maintenance dose is administered via subcutaneous injection once every 6 months, regardless of the initial regimen used. Healthcare providers should determine the appropriate initial regimen for each patient. Lenacapavir oral tablets can be taken with or without food.
FDA，2024.11
