Your Health, We Care
Release date: 2024-08-23 14:58:04 Recommended: 129
Koselugo is an anti-cancer drug targeting MEK protein, which can successfully block cell signaling pathways and inhibit the proliferation of tumor cells, with significant and superior efficacy for specific cancer types.
During the use of Koselugo, the following should be noted:
Pay attention to creatine phosphokinase levels, regularly measure serum CPK, check for rhabdomyolysis and other risks if abnormally elevated, and adjust medication if necessary;
Be alert to bleeding tendency, especially when combined with vitamin K antagonists, strengthen bleeding monitoring, adjust the dose of anticoagulant drugs, and ensure patient safety.
When using Koselugo, we must pay close attention to the potential risks and precautions to ensure that the treatment is safe and effective. Developing and responding to possible elevated creatine phosphokinase is essential to prevent and treat these complications.
Creatine phosphokinase is elevated in patients with Koselugo and coping includes:
Discontinue or taper the drug immediately, and closely monitor CPK levels to assess the extent of muscle damage;
Conduct a comprehensive physical examination, especially focusing on symptoms such as muscle pain and weakness, investigate potential causes such as rhabdomyolysis, and take targeted treatment measures such as rehydration and diuresis if necessary to protect the patient's muscle function and overall health.
Creatine phosphokinase elevation in patients with Koselugo requires prompt measures to reduce the potential risk. Similarly, we should develop strategies to deal with the risk of bleeding that may arise in advance to ensure that the patient passes through the treatment period safely.
Patients are at increased risk of bleeding after Koselugo and coping include:
Strengthen bleeding monitoring, regularly check the bleeding of patients, such as bleeding gums, skin ecchymosis, etc., and detect and treat them in time;
Adjust the dose of anticoagulant drugs, and for patients taking vitamin K antagonists or antiplatelet drugs, the dose of drugs should be adjusted according to indicators such as INR or prothrombin time to reduce the risk of bleeding and ensure patient safety.
【Warm tips】When patients buy generic drugs, they should choose formal channels to ensure the quality and safety of the drugs. Avoid purchasing counterfeit products from informal sources.
