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Tivozanib is an oral VEGFR tyrosine kinase inhibitor (TKI), which is an effective and selective inhibitor of VEGFRs 1, 2, and 3. The FDA has approved Tivozanib/Fotivda for the treatment of adult recurrent or refractory advanced renal cell carcinoma (RCC) patients who have received two or more systemic therapies.
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