Your Health, We Care
Release date: 2024-11-21 15:45:39 Recommended: 85
Gireltinib is primarily effective in acute myeloid leukemia (AML), particularly in relapsed or refractory AML harboring FLT3 mutations.
Gireltinib is a novel, highly selective oral FLT3 inhibitor. It inhibits FLT3 mutant isoforms (ITD and TKD) and also inhibits the activity of the tyrosine kinase AXL, which is associated with FLT3 inhibitor resistance.
Gilitinib significantly improves the survival of FLT3 patients with acute myeloid leukemia Clinical trials have shown that the FLT3 inhibitor Gilteritinib has significant efficacy in the treatment of FLT3-mutated patients with acute myeloid leukemia, and the overall survival of patients has been greatly improved.
Compared with traditional chemotherapy methods, the response rate of geritinib in terms of complete response (CR), CR of hematologic recovery, and overall response was significantly improved, and some data even doubled. In addition, it is worth noting that the transplantation rate of patients treated with gilitinib was as high as 26%, which was significantly higher than the 15% in the chemotherapy group. The duration of treatment with gilitinib in these patients is also considerable.
The data further confirmed that the median survival (OS) of patients treated with gilitinib was 9.3 months, compared to 5.6 months in the chemotherapy group, a statistically significant difference. At the same time, the one-year OS rate in the giritinib-treated group also doubled. Overall, gilitinib demonstrated superior efficacy over chemotherapy in all response measures.
Generic products for giritinib are subject to strict quality control and regulatory approvals in terms of efficacy and safety to ensure that they meet relevant standards and requirements. Although generic drugs are similar to the original drug in terms of active ingredients, dosage forms, and route of administration, there may be differences in quality control, impurity control, and excipient selection during the manufacturing process, so it is necessary to follow the doctor's advice and guidance when using them.
When choosing to purchase a generic version of gilitinib, patients may consider the following avenues:
1. Purchase through formal overseas medical consulting institutions in China, which often have established cooperation with overseas pharmaceutical companies to help patients directly purchase overseas drugs.
2. Patients or their relatives and friends can travel directly to the country where the generic drug is produced, such as Bangladesh or Laos, and purchase it through a local official pharmacy or hospital pharmacy.
3. Use a certified online pharmacy to buy, but double-check the pharmacy's credentials to ensure that the source of the medicine is legitimate and legitimate.
