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What is the recommended dosage of Fidaxomicin?

Release date: 2024-08-29 15:02:25     Recommended: 152

Fidaxomicin is a macrolide antibiotic from Optimer, which brings an efficient and safe treatment regimen for patients with refractory Clostridium infection with its unique RNA polymerase inhibition mechanism, opening a new era of anti-infection.

What is the recommended dosage of Fidaxomicin?

The recommended dose of Fidaxomicin mainly includes the following two points:

1. Standard dose

For most adult patients, the recommended dose of Fidaxomicin is 200 mg orally twice daily for 10 days. This is based on clinical trials and aims to provide the best possible outcome for adult patients.

2. Adjustment of special populations

For special populations, such as older adults, people with liver and kidney insufficiency, and children with low body weight, doctors may adjust the dose appropriately according to the patient's specific situation. However, this is also up to the doctor on a case-by-case basis.

The recommended dose of Fidaxomicin is 200 mg twice daily. During the period of taking Fidaxomicin, it is necessary to closely monitor liver and kidney function, blood routine, and stool markers to ensure the safety and efficacy of the drug.

What indicators need to be tested while taking Fidaxomicin

While taking Fidaxomicin, there are two key indicators that need to be closely monitored:

1. Liver function indicators

These include serum aminotransferases (eg, ALT, AST) and bilirubin levels. Fidaxomicin may cause abnormal liver function, and regular testing of these markers can help detect and manage potential liver damage.

2. Complete blood count

In particular, the white blood cell count and neutrophil ratio. Fidaxomicin may cause hematologic adverse effects, such as neutropenia, and monitoring a complete blood count can help assess the patient's blood health.

During the period of taking Fidaxomicin, liver and kidney function, blood routine, and stool markers should be monitored. During the medication, avoid taking it with other drugs, pay attention to dietary habits, and follow the doctor's instructions to ensure that the medication is safe and effective.

Precautions during the administration of Fidaxomicin

While taking Fidaxomicin, you should pay attention to the following two points:

1. Regular monitoring

It is important to monitor liver function and blood routine regularly as prescribed by your doctor to detect and manage possible adverse effects in a timely manner.

2. Avoid interactions

Inform your doctor of all medications you are taking, including prescription drugs, over-the-counter medications, supplements, and herbal remedies, to prevent drug-drug interactions that could affect the efficacy of Fidaxomicin or increase the risk of adverse effects. At the same time, alcohol should be avoided during the medication to avoid increasing the burden on the liver.

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