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Drug interactions of Everolimus

Effects of Other Drugs on Everolimus:

Inhibitors: Avoid concurrent use with P-glycoprotein (P-gp) and strong CYP3A4 inhibitors. Dosage reduction is required when coadministered with P-gp and moderate CYP3A4 inhibitors.

Inducers: Dosage increase is required when coadministered with P-gp and strong CYP3A4 inducers.

Effects of Concurrent Use with ACE Inhibitors:

Concurrent use may increase the risk of angioedema. Avoid concurrent use.

FDA，2022.02