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Adverse reactions of Encorafenib

1. New primary malignant tumors.

2. Promotion of BRAF wild-type tumor growth.

3. Cardiomyopathy.

4. Hepatotoxicity.

5. Bleeding.

6. Uveitis.

7. QT interval prolongation.

8. Embryo-fetal toxicity.

9. Risks of BRAFTOVI monotherapy.

10. Risks of combination therapy.

FDA，2025.03