Your Health, We Care
Release date: 2025-03-25 10:53:29 Recommended: 72
Proper use of eltrombopag requires a combination of medical guidance and individualized needs.
Knowing the details of your medications can help improve the quality of treatment and reduce potential risks.
Initial medication should be individualized based on the patient's body weight and platelet count. During treatment, blood markers should be monitored regularly to avoid the risk of blood clots caused by excessive doses. If the platelet count exceeds the target range, the drug should be discontinued and the physician should be consulted to reevaluate the regimen.
Patients with hepatic insufficiency need to adjust the initial dose to 25% of the regular dosage, and patients with severe liver injury should be disabled. Use during pregnancy may affect the fetal hematopoietic system, and breastfeeding should be suspended in lactating women. Elderly patients need to strengthen dynamic monitoring of liver and kidney function.
Combination with anticoagulants may increase the risk of bleeding and should be taken more than 4 hours apart. Calcium-containing and iron-containing preparations will reduce the absorption rate of the drug, and it is recommended to take them at least 2 hours apart. Some antibiotics may alter the rate of metabolism, and platelet testing should be increased during the combination.
Improving the benefits of treatment requires multi-dimensional collaborative management.
Myelofibrosis screening and baseline assessment of liver function should be completed prior to treatment. Complete blood count is performed weekly for the first 8 weeks and monthly during stable periods. Liver enzyme testing is done every 3 months, and protective therapy should be initiated immediately if abnormal values occur.
A maintenance dose strategy was used for sustained responders, with quality of life indicators assessed at regular intervals. Some responders require combination immunomodulatory therapy, and genetic testing is recommended for refractory cases. Establish a patient medication diary to record platelet fluctuations and symptom changes.
It is recommended to take the drug on an empty stomach in the morning. The principle of missing the dose can be clarified, and the dose can be retaken within 12 hours, and the current dose can be skipped if it is overtimed. Make a visual medication reminder card to mark the adverse reaction reporting process and emergency contact information.
Scientific drug use requires the coordination of doctors and patients, from dose control to full monitoring, forming a complete management closed loop. Through precise program design and dynamic index tracking, the treatment benefit can be maximized.
