Your Health, We Care
Release date: 2024-11-13 14:08:54 Recommended: 121
Elacestrant, a non-steroidal small molecule, is an estrogen receptor (ER) antagonist. Erastratran binds to estrogen receptor α (ERα) and acts as a selective estrogen receptor degrader (SERD), able to block the transcriptional activity of ER and promote its degradation, and the use of SERD represents a treatment for endocrine-resistant breast cancer.
Erastratran generic drugs are not currently available in China, and you may need to go to the countries where the generic drugs are listed to purchase them.
At present, it is known that the generic drug of Erastratran is produced in Lucius, Laos, and patients can go to the local hospital for treatment, and wait for the doctor to prescribe the drug directly in the hospital's pharmacy.
This version of the drug may be sold in local pharmacies in countries where the generic version of elastrant is marketed, and it is recommended to present a medical prescription before purchasing.
Some health care providers in China may be able to help with the purchase of generic drugs, and you can ask if they can help you buy generic ellastrants.
Patients must choose formal channels to avoid purchasing drugs through illegal channels, such as informal websites, personal purchasing, etc., the drugs in these channels may have safety risks, and they should also understand the price of alastitran drugs in many aspects before purchasing drugs
At present, it is understood that there are 2 specifications of the Elasi group imitated by Lucius Laos, and the specifications are different, and the price is also different. The price of a box of 86mg*30 tablets of iralastrant is about 3780 yuan-4200 yuan, and the price of a box of 345mg*30 tablets of iralastrant is about 10800 yuan-11200 yuan.
Compared with the original drug of elastrant, the price of the generic drug of alalastrant will be cheaper, which can reduce the medical economic burden of patients.
The oral bioavailability of alalastrant is approximately 10%, and its plasma protein binding rate exceeds 99%, independent of concentration. Erastratran is metabolized in the liver, mainly by the cytochrome P450 enzyme CYP3A4, followed by CYP2A6 and CYP2C9. Erastratran has an elimination half-life of 30-50 hours and is excreted mainly in feces (82%) and secondarily in urine (7.5%).
The most common side effects of elastrant include body aches, nausea, vomiting, increased blood lipids, increased liver enzymes, fatigue, decreased hemoglobin, increased creatinine, decreased appetite, etc.
