1. Myelosuppression.
2. Bleeding-related events.
3. Fluid retention.
4. Cardiovascular toxicity.
5. Pulmonary arterial hypertension.
6. QT interval prolongation.
7. Severe cutaneous reactions.
8. Tumor lysis syndrome.
9. Effects on growth and development in pediatric patients.
10. Hepatotoxicity.
FDA,2024.07