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Drug interactions of Capivasertib

Strong CYP3A Inhibitors:

Avoid concomitant use with strong CYP3A inhibitors. If concomitant use is unavoidable, reduce the dose of capmatinib and monitor the patient for adverse reactions.

Moderate CYP3A Inhibitors:

When used concomitantly with moderate CYP3A inhibitors, reduce the dose of capmatinib and monitor the patient for adverse reactions.

Strong or Moderate CYP3A Inducers:

Avoid concomitant use of capmatinib with strong or moderate CYP3A inducers.

from FDA，2024.09