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For which diseases is Capivasertib indicated?

Release date: 2026-01-13 17:00:53     Recommended: 82

Capivasertib in combination with fulvestrant can be used as a second-line or third-line treatment regimen for patients with metastatic breast cancer who are hormone receptor-positive, human epidermal growth factor receptor 2-negative, and harbor PIK3CA/AKT1 gene mutations or PTEN gene inactivation.

For which diseases is Capivasertib indicated?

Capivasertib in combination with fulvestrant (Faslodex) is indicated for the treatment of adult patients with locally advanced or metastatic breast cancer who are hormone receptor-positive, human epidermal growth factor receptor 2-negative, and have at least one PIK3CA/AKT1/PTEN gene mutation confirmed by an FDA-approved test. This indication applies to patients whose disease has progressed after receiving at least one endocrine-based therapy in the metastatic setting, or who have experienced recurrence within 12 months or later after completion of adjuvant therapy.

What should be known about the storage and disposal of this medication?

Store this medication in its original packaging container, tightly close the bottle cap, and keep it out of the reach of children. Store at room temperature, away from excessive heat and moisture (do not store in the bathroom).

Keep all medications out of sight and reach of children, as many containers are not child-resistant. Always lock the safety cap. Store medications in a secure location that is both inaccessible and invisible to them.

Dispose of unused medications in a manner that is inaccessible to pets, children, and other individuals. Do not flush this medication down the toilet. Utilize a medication take-back program. Consult your pharmacist for information on medication take-back programs available in your community.

What other information should be known?

1. Keep all appointments with your doctor and laboratory. Your doctor will order certain laboratory tests before and during your treatment to monitor your body’s response to capivasertib.

2. Your doctor will order a laboratory test before you start treatment to determine if your cancer is suitable for treatment with capivasertib.

3. Do not share this medication with others. If you have any questions about prescription refills, consult your pharmacist.

4. Maintain a written list of all prescription and over-the-counter medications, vitamins, minerals, and dietary supplements you are taking. Bring this list with you every time you visit your doctor or are admitted to the hospital. You should carry this list with you at all times for emergencies.