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Indications of Capivasertib

Capivasertib, in combination with fulvestrant, is indicated for the treatment of adult patients with hormone  receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or  metastatic breast cancer with one or more PIK3CA/AKT1/PTEN-alteration as detected by an FDAapproved test following progression on at least one endocrine-based regimen in the metastatic setting or  recurrence on or within 12 months of completing adjuvant therapy.

from FDA,2024.09

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