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What are the side effects of cabozantinib use?

Release date: 2025-02-20 13:29:42     Recommended: 88

Cabozantinib is a multi-targeted tyrosine kinase inhibitor that has shown significant efficacy in the treatment of a variety of cancers, but its accompanying side effects are also of concern.

What are the side effects of cabozantinib use?

Understanding the potential side effects of cabozantinib is critical for patients and physicians to develop the appropriate treatment plan.

Skin-related side effects

Common skin side effects of cabozantinib include hand-foot syndrome, which is characterized by redness, pain, and blisters on the palms and soles of the feet. In addition, some patients may experience symptoms such as dry skin, itching, or a rash. These skin reactions usually occur early in treatment and may worsen as treatment continues.

Digestive side effects

The digestive system is also a common site of carbobrutinib side effects. Patients may present with symptoms such as diarrhea, nausea, vomiting, and decreased appetite. These symptoms can lead to weight loss, malnutrition, and even adherence to treatment.

Metabolic and cardiovascular side effects

Cabozantinib may also cause metabolic and cardiovascular side effects such as hypertension and hypophosphatemia. High blood pressure is one of the most common cardiovascular side effects of cabozantinib treatment and may increase the risk of heart disease and stroke. During cabozantinib use, patients should monitor their blood pressure regularly and adjust their antihypertensive medications as needed.

How to manage cabozantinib side effects?

Effective management of cabozantinib side effects can improve the treatment experience and efficacy of patients.

Skin care and moisturizing

For skin side effects such as hand-foot syndrome, patients can relieve symptoms by keeping their skin clean and dry, avoiding friction and pressure, and using a gentle moisturizer. Your doctor may recommend specific skin care products or medications if necessary.

Dietary modification and nutritional support

For digestive side effects, patients can try to improve symptoms by dividing meals, eating easily digestible foods, and avoiding greasy and spicy foods. For people with decreased appetite and weight loss, your doctor may recommend increased nutrient intake, such as a high-protein diet or enteral nutrition support.

Regular monitoring and medication adjustments

In order to detect and deal with the metabolic and cardiovascular side effects of cabozantinib in a timely manner, patients should regularly monitor blood pressure, blood phosphorus and other indicators. If there is an abnormality, your doctor may adjust the dose of cabozantinib or add the appropriate treatment drugs.

Cabozantinib is an effective anti-cancer drug, and its side effects cannot be ignored. By understanding and managing these side effects, patients can improve their quality of life while maintaining the effectiveness of their treatment. During the use of cabozantinib, patients should pay close attention to the changes in their symptoms and maintain close communication with their doctor to jointly develop a personalized treatment plan.