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Adverse reactions of Binimetinib

Melanoma: Most common adverse reactions (≥25%) for MEKTOVI, in  combination with encorafenib, are fatigue, nausea, diarrhea, vomiting, and  abdominal pain.

NSCLC: Most common adverse reactions (≥25%) for MEKTOVI, in  combination with encorafenib, are fatigue, nausea, diarrhea,  musculoskeletal pain, vomiting, abdominal pain, visual impairment,  constipation, dyspnea, rash, and cough.

from FDA，2024.09