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Side Effects of Afatinib

Release date: 2026-03-31 17:08:17     Recommended: 6

Awareness of these potential side effects helps patients identify them early and take timely intervention measures. However, it should be noted that the assessment and management of any side effects must be carried out under the professional guidance of a doctor.

Serious Side Effects

More Common

Blood in urine or cloudy urine, burning, dryness or itching of the eyes, diarrhea, difficult, burning or painful urination, increased eye discharge or excessive tearing, fever, frequent urination, redness, pain or swelling of the eyes, eyelids or conjunctiva, redness, swelling or pain of the skin, skin peeling of the hands and feet, numbness of the hands and feet, skin ulcers.

Less Common

Cough, dyspnea.

Rare

Blood in stools, black or tarry stools, heartburn, indigestion, nausea, severe abdominal pain, abdominal cramps or burning sensation in the abdomen, coffee-ground-like vomitus (with severe and persistent symptoms).

Seek immediate emergency medical attention if any of the following overdose symptoms occur during treatment:

Overdose Symptoms

Dizziness, headache, fatigue or weakness, abdominal pain, vomiting.

Other Side Effects

More Common

Skin blemishes, oral ulcers, chapped, red or swollen lips, decreased appetite, weight loss, dry skin, skin itching or rash, loose nails, nosebleeds, acne, redness or pain around the nails, runny nose, chapped, red, burning, painful or other inflammatory manifestations of the lips, ulcers or erosions on the lips, tongue or inside the mouth.