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Therapeutic efficacy of Afatinib

1 EGFR Mutation-Positive, Metastatic NSCLC

A statistically significant improvement in PFS as determined by the IRC was demonstrated for patients  randomized to Afatinib compared with those randomized to chemotherapy. See Table 5 and Figure 1. There was no statistically significant difference for OS between the treatment arms at the final  pre-planned analysis.

from FDA，2022.04